929099-11-6Relevant articles and documents
Synthesis of diazirine-based photoreactive saccharin derivatives for the photoaffinity labeling of gustatory receptors
Wang, Lei,Yoshida, Takuma,Muto, Yasuyuki,Murai, Yuta,Tachrim, Zetryana Puteri,Ishida, Akiko,Nakagawa, Shiori,Sakihama, Yasuko,Hashidoko, Yasuyuki,Masuda, Katsuyoshi,Hatanaka, Yasumaru,Hashimoto, Makoto
, p. 3129 - 3134 (2015/05/13)
Saccharin is one of the most common artificial sweeteners that has a bitter taste at high concentrations. Currently, there are no detailed functional analyses of these gustatory receptors. Therefore, we designed and synthesized photoreactive saccharin der
Alternative one-pot synthesis of (trifluoromethyl)phenyldiazirines from tosyloxime derivatives: Application for new synthesis of optically pure diazirinylphenylalanines for photoaffinity labeling
Wang, Lei,Murai, Yuta,Yoshida, Takuma,Ishida, Akiko,Masuda, Katsuyoshi,Sakihama, Yasuko,Hashidoko, Yasuyuki,Hatanaka, Yasumaru,Hashimoto, Makoto
supporting information, p. 616 - 619 (2015/03/04)
Alternative one-pot synthesis of 3-(trifluoromethyl)-3-phenyldiazirine derivatives from corresponding tosyloximes is developed. The deprotonation of intermediate diaziridine by NH2- is a new approach for construction of diazirine. Moreover, a novel synthesis of optically pure (trifluoromethyl)diazirinylphenylalanine derivatives was attempted involving these methods.
NSAID-derived γ-secretase modulators. Part III: Membrane anchoring
Baumann, Stefanie,Hoettecke, Nicole,Schubenel, Robert,Baumann, Karlheinz,Schmidt, Boris
supporting information; experimental part, p. 6986 - 6990 (2010/06/19)
Selective lowering of Aβ42 levels with small-molecule substrate targeting γ-secretase modulators (sGSMs), such as some non-steroidal anti-inflammatory drugs, is a promising therapeutic approach for Alzheimer's disease. Here we present N-substit
