929202-11-9Relevant articles and documents
SAR studies of 3-arylpropionic acids as potent and selective agonists of sphingosine-1-phosphate receptor-1 (S1P1) with enhanced pharmacokinetic properties
Yan, Lin,Huo, Pei,Hale, Jeffrey J.,Mills, Sander G.,Hajdu, Richard,Keohane, Carol A.,Rosenbach, Mark J.,Milligan, James A.,Shei, Gan-Ju,Chrebet, Gary,Bergstrom, James,Card, Deborah,Mandala, Suzanne M.
, p. 828 - 831 (2007/10/03)
Structure-activity relationship (SAR) studies of 3-arylpropionic acids-a class of novel S1P1 selective agonists-by introducing substitution to the propionic acid chain and replacing the adjacent phenyl ring with pyridine led to a series of modi