92934-90-2

Upstream product

• 83651-48-3 7-(tert-Butyl-dimethyl-silanyloxy)-2,6-dimethyl-heptan-1-ol 
• 98-59-9 p-toluenesulfonyl chloride 
• 92803-69-5 ((R)-1-Phenyl-ethyl)-carbamic acid (2S,6R)-7-hydroxy-2,6-dimethyl-heptyl ester 
• 92803-67-3 ((S)-1-Phenyl-ethyl)-carbamic acid (R)-2-[(1S,3R)-2,2-dibromo-3-((S)-2-hydroxy-1-methyl-ethyl)-cyclopropyl]-propyl ester 
• 92803-68-4 ((S)-1-Phenyl-ethyl)-carbamic acid (2R,6S)-7-hydroxy-2,6-dimethyl-hepta-3,4-dienyl ester 
• 92803-72-0 ((R)-1-Phenyl-ethyl)-carbamic acid (2S,6R)-7-(tert-butyl-dimethyl-silanyloxy)-2,6-dimethyl-heptyl ester 
• 92934-86-6 ((S)-1-Phenyl-ethyl)-carbamic acid (S)-2-[(1S,3R)-2,2-dibromo-3-((R)-2-hydroxy-1-methyl-ethyl)-cyclopropyl]-propyl ester 
• 92803-68-4 ((S)-1-Phenyl-ethyl)-carbamic acid (2S,6R)-7-hydroxy-2,6-dimethyl-hepta-3,4-dienyl ester 
• 92934-87-7 ((S)-1-Phenyl-ethyl)-carbamic acid (2S,6R)-7-hydroxy-2,6-dimethyl-heptyl ester 
• 92803-72-0 ((S)-1-Phenyl-ethyl)-carbamic acid (2S,6R)-7-(tert-butyl-dimethyl-silanyloxy)-2,6-dimethyl-heptyl ester 
• 173690-81-8 (2R,6S)-7-acetoxy-2,6-dimethyl-1-heptanol 
• 173690-84-1 Acetic acid (2S,6R)-7-(tert-butyl-dimethyl-silanyloxy)-2,6-dimethyl-heptyl ester 
• 40325-99-3 2,6-dimethyl-1,7-heptanediol 
• 375844-64-7 (2R,4RS,6S)-1-tert-butyldimethylsilyloxy-2,6-dimethyl-4-phenylsulfonyl-7-tetrahydropyranyloxyheptane 

Downstream Products

• 375844-70-5 (2R,6R)-2,6-dimethyl-1-tert-butyldimethylsilyloxy-17-octadecene 
• 112965-78-3 (S)-Methoxy-phenyl-acetic acid (2R,6R)-2,6,10-trimethyl-undecyl ester 
• 375844-83-0 (2R,6R)-2,6-dimethyl-17-octadecenyl p-toluenesulfonate 

Relevant academic research and scientific papers

Enzymatic desymmetrization of meso-2,6-dimethyl-1,7-heptanediol. Enantioselective formal synthesis of the vitamin E side chain and the insect pheromone tribolure

The chiral syn-1,5-dimethylalkyl subunit is found in many natural products with significant biological activities. Enzymatic esterification of meso-2,6-dimethyl-1,7-heptanediol with isopropenyl acetate in the presence of Pseudomonas cepacia lipase in organic medium provided the chiral nonracemic monoester in high enantiomeric excess (ee = 95%). This chiral building block was used in the formal syntheses of vitamin E side chain and the insect pheromone tribolure.

Synthesis of all the stereoisomers of 13,17-dimethyl-1-tritriacontene and 13,17-dimethyl-1-pentatriacontene, the contact sex pheromone components of the female tsetse fly, Glossina austeni

All of the stereoisomers of 13,17-dimethyl-1-tritriacontene (1) and 13,17-dimethyl-1-pentatriacontene (2), the contact sex pheromone components of the female tsetse fly (Glossina austeni), were synthesized starting from the enantiomers of the protected syn- and anti-2,6-dimethylheptane-1,7-diol (3), which were prepared from the enantiomers of methyl 3-hydroxy-2-methylpropanoate (4) and methyl phenyl sulfone (5).

ACYCLIC STEREOSELECTION. 15. SEQUENTIAL ALDOL-CLAISEN AS A METHOD FOR 1,5-STEREOSELECTION. TOTAL SYNTHESIS OF THE VITAMIN-E SIDE CHAIN

Alcohol 1, the side chain of α-tocopherol, has been synthesized in a stereoselective route involving an aldol condensation-Claisen rearrangement sequence.The synthesis requires 11 steps and produces 1 in 17percent overall yield.A complementary sequence em