92948-25-9Relevant academic research and scientific papers
New efficient imidazolium aldoxime reactivators for nerve agent-inhibited acetylcholinesterase
Wei, Zhao,Liu, Yan-Qin,Zhou, Xin-Bo,Luo, Yuan,Huang, Chun-Qian,Wang, Yong-An,Zheng, Zhi-Bing,Li, Song
supporting information, p. 5743 - 5748 (2015/01/09)
Herein, we described a new class of uncharged non-pyridinium reactivators for nerve agent-inhibited acetylcholinesterase (AChE). Based on a dual site binding strategy, we conjugated the imidazolium aldoxime to different peripheral site ligands (PSLs) of A
Pheromone synthesis. Part 243: Synthesis and biological evaluation of (3R,13R,1′S)-1′-ethyl-2′-methylpropyl 3,13-dimethylpentadecanoate, the major component of the sex pheromone of Paulownia bagworm, Clania variegata, and its stereoisomers
Mori, Kenji,Tashiro, Takuya,Zhao, Boguang,Suckling, David M.,El-Sayed, Ashraf M.
experimental part, p. 2642 - 2653 (2010/05/18)
All of the four stereoisomers of (1′S)-1′-ethyl-2′-methylpropyl 3,13-dimethylpentadecanoate, the major component of the female sex pheromone of Clania variegata, were synthesized by employing olefin cross metathesis as the key reaction and starting from (R)- or (S)-2-methyl-1-butanol, (R)- or (S)-citronellal, and (S)-2-methyl-3-pentanol. Their bioassay revealed the (3R,13R,1′S)-isomer as the bioactive one, whose more efficient synthesis was achieved in two different ways by employing Wittig reaction as the key step.
3- and 4-biphenyloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents
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, (2008/06/13)
Compounds useful for treating inflammation, swelling and associated pain, represented by the formula: STR1 and the pharmaceutically acceptable acid addition salts thereof, wherein: a is an integer of 0-3; b is an integer of 0-2; n is an integer of 3-12; each X and each Y are independently -halo, --R1, -alkoxy, or -phenyl; and B is selected from the group consisting of: --NR1 R2, --NR1 (CH2 CH2 OH), STR2 in which R1 and R2 are independently H, alkyl or cycloalkyl; R3 is H, alkyl or --CH2 CH2 OH; and m is an integer of 3-8. Novel compounds are those wherein n is at least 6 if both a and b are 0.
Anti-inflammatory guanidines
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, (2008/06/13)
A compound having the formula STR1 where Ar=naphthyl, biphenyl, or quinolinyl; X=oxygen or NH; Y=2 to 8; R1 =phenyl, substituted phenyl, hydrogen, lower alkyl; and R2 is the same or different from R3 and is alkyl, cycloalkyl, phenyl, substituted phenyl, thiazolyl; and the pharmaceutically acceptable salts thereof. Compounds of this general formula are useful as anti-inflammatories, and as anti-psoriatic agents.
