92950-41-9Relevant articles and documents
Organocatalytic site-selective acylation of 10-deacetylbaccatin III
Yanagi, Masanori,Ninomiya, Ryo,Ueda, Yoshihiro,Furuta, Takumi,Yamada, Takeshi,Sunazuka, Toshiaki,Kawabata, Takeo
, p. 907 - 912 (2016/07/14)
Organocatalytic site-selective diversification of 10-deacetylbaccatin III, a key natural product for the semisynthesis of taxol, has been achieved. Various acyl groups were selectively introduced into the C(10)-OH of 10-deacetylbaccatin III. The C(10)-OH selective acylation was also applied to acylative site-selective dimerization of 10-deacetylbaccatin III to provide the structurally defined dimer.