92952-81-3

Basic information

• Product Name: 3-Nitro-N-(2-hydroxypropyl)-4-aminophenol
• Synonyms: 4-HYDROXYPROPYLAMINO-3-NITROPHENOL;4-(3-HYDROXYPROPYLAMINO)-3-NITROPHENOL;3-NITRO-N-(2-HYDROXYPROPYL)-4-AMINOPHENOL;3-NITRO-4-HYDROXYPROPYLAMINOPHENOL;3-NITRO-4-HYDROXYPROPYLPHENOL;4-hydroxypropylamino-3-nitrophenol,4-hydroxypropylamino-2-nitrophenol;4-Hydroxypropylamino-3-Nitrophenol (HC RED BN);3-Nitro-N-(2-hydroxypropyl)-4-aminophenol (HC Red BN)
• CAS NO: 92952-81-3
• Molecular Formula: C9H12N2O4
• Molecular Weight: 212.2
• EINECS: 406-305-9
• Mol File: 92952-81-3.mol
• Article Data: 2

Chemical Properties

• Melting Point: 108-109℃
• Boiling Point: 464.7 °C at 760 mmHg
• Flash Point: 234.8 °C
• Appearance: Dark red crystal powder
• Density: 1.414 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.655
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 9.43±0.14(Predicted)
• CAS DataBase Reference: 3-Nitro-N-(2-hydroxypropyl)-4-aminophenol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Nitro-N-(2-hydroxypropyl)-4-aminophenol(92952-81-3)
• EPA Substance Registry System: 3-Nitro-N-(2-hydroxypropyl)-4-aminophenol(92952-81-3)

Safety Data

• Hazard Codes: Xi,N
• Statements: 38-51/53
• Safety Statements: 37-61
• Hazardous Substances Data: 92952-81-3(Hazardous Substances Data)

Usage

Flammability and Explosibility

Nonflammable

InChI:InChI=1/C9H12N2O4/c1-2-9(13)10-7-4-3-6(12)5-8(7)11(14)15/h3-5,9-10,12-13H,2H2,1H3

Upstream product

• 92952-83-5 3-nitro-4-(3-chloropropoxycarbonylamino)phenol 
• 610-81-1 4-hydroxy-2-nitroaniline 
• 628-11-5 3-chloropropyl chloroformate 

Relevant articles and documents

3-nitro-4-hydroxy-propyl-aminophenol method for the preparation of

The invention relates to a preparation method of 3-nitro-4-hydroxypropyl aminophenol. The method comprises the following steps: (1) carrying out a condensation reaction on 3-nitro-4-aminophenol and propyl chlorocarbonate under the action of calcium carbonate by taking 80% to 90% dioxane aqueous solution as a solvent; (2) dropwise adding alkali liquor with the mass concentration being 40% to 55% and carrying out a hydrolysis reaction by controlling a dropwise adding temperature within 50 DEG C to 55 DEG C, then reacting at 58 DEG C to 65 DEG C for 0.5 to 5 hours in a heat preservation manner, cooling to 30 DEG C to 40 DEG C, regulating pH to reach 5.5 to 6.5 and removing ethyl alcohol by evaporating so as to obtain a crude product of the 3-nitro-4-hydroxypropyl aminophenol; and (3) pulping the crude product of the 3-nitro-4-hydroxypropyl aminophenol in an n-propyl alcohol aqueous solution with the mass concentration being 18% to 22% so as to obtain the 3-nitro-4-hydroxypropyl aminophenol. According to the method, the total yield of the 3-nitro-4-hydroxypropyl aminophenol can reach above 90%, and the reactions in the two steps can be carried out in a manner of one-pot synthesis, so that the method has the advantages of being simple in production operation, fewer in byproducts, high in 3-nitro-4-hydroxypropyl aminophenol quality, less in pollution, low requirement on equipment and the like.