Bulgecin A, a natural product derived from the Streptomyces bacterial strain, is a potent inhibitor of bacterial cell wall synthesis. It exhibits activity against various antibiotic-resistant bacteria by inhibiting the enzyme MurG, which is essential for the synthesis of peptidoglycan, a major component of the bacterial cell wall. This disruption of the bacterial cell wall formation leads to cell death, making bulgecin A a promising candidate in the development of new antibiotics to combat antibiotic resistance.
92953-54-3
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Basic information
- Product Name: bulgecin A
- Synonyms: bulgecin A
- CAS NO:92953-54-3
- Molecular Formula: C16H29 N3 O14 S2
- Molecular Weight: 551.54
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: °Cat760mmHg
- Flash Point: °C
- Appearance: /
- Density: 1.72g/cm3
- Refractive Index: 1.63
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: bulgecin A(CAS DataBase Reference)
- NIST Chemistry Reference: bulgecin A(92953-54-3)
- EPA Substance Registry System: bulgecin A(92953-54-3)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 92953-54-3(Hazardous Substances Data)
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92953-54-3 Usage
Uses
Used in Pharmaceutical Industry:Bulgecin A is used as an antibacterial agent for its effectiveness against antibiotic-resistant bacteria. Its ability to inhibit the enzyme MurG and disrupt the formation of the bacterial cell wall makes it a valuable asset in the search for new antibiotics to address the growing threat of antibiotic resistance.
Used in Drug Development:
Bulgecin A is used as a lead compound in the development of new antibiotics. Its unique mechanism of action targeting the MurG enzyme and its activity against a variety of antibiotic-resistant bacteria make it a promising candidate for further research and development in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 92953-54-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,2,9,5 and 3 respectively; the second part has 2 digits, 5 and 4 respectively.Calculate Digit Verification of CAS Registry Number 92953-54:
(7*9)+(6*2)+(5*9)+(4*5)+(3*3)+(2*5)+(1*4)=163
163 % 10 = 3
So 92953-54-3 is a valid CAS Registry Number.
InChI:InChI=1/C16H29N3O14S2/c1-7(22)18-12-13(23)14(33-35(28,29)30)11(6-21)32-16(12)31-10-4-8(19-9(10)5-20)15(24)17-2-3-34(25,26)27/h8-14,16,19-21,23H,2-6H2,1H3,(H,17,24)(H,18,22)(H,25,26,27)(H,28,29,30)
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bulgecin A
