929554-27-8Relevant academic research and scientific papers
New N-substituted dipolarophiles in 1,3-dipolar cycloaddition of nitrones
Nguyen, Thanh Binh,Gaulon, Catherine,Chapin, Teddy,Tardy, Sébastien,Tatibou?t, Arnaud,Rollin, Patrick,Dhal, Robert,Martel, Arnaud,Dujardin, Gilles
, p. 3255 - 3258 (2006)
(N-Vinyl)-1,3-oxazolidin-2-ones, -1,3-oxazolidine-2-thiones and -N′-methylimidazolidin-2-one were conveniently used as new dipolarophiles in thermal 1,3-dipolar cycloaddition involving activated nitrones, and led to new 5-N-substituted isoxazolidines in high yields. A moderate to total trans-diastereoselectivity was observed, increasing with the degree of substitution at C-4. Georg Thieme Verlag Stuttgart.
