929563-05-3Relevant academic research and scientific papers
Palladium-catalyzed intramolecular hydroamination of propargylic carbamates and carbamothioates
Alamsetti, Santosh Kumar,Persson, Andreas K. A.,Baeckvall, Jan-E.
, p. 1434 - 1437 (2014/04/03)
An efficient and simple methodology was developed for the synthesis of oxazolidinones, oxazolidinthiones, imidazolidinthiones, and imidazolidinones from the corresponding propargylic starting materials using Pd(OAc)2 and n-Bu4NOAc as catalysts in DCE at room temperature.
Scalable synthesis of oxazolones from propargylic alcohols through multistep palladium(II) catalysis: β-selective oxidative heck coupling of cyclic sulfonyl enamides and aryl boroxines
Alamsetti, Santosh Kumar,Persson, Andreas K. A.,Jiang, Tuo,Baeckvall, Jan-E.
, p. 13745 - 13750 (2014/01/06)
A whale of a scale: The title oxidative Heck coupling proceeded with unusual β selectivity to generate a variety of branched substituted oxazolones (see scheme; Ts=p-toluenesulfonyl). The three-step synthesis from readily available starting materials with a simple palladium catalyst and inexpensive reagents could be carried out in a single reaction vessel or scaled up for the preparation of large amounts of these amino acid precursors. Copyright
Gold-catalyzed cyclization of O-propargyl carbamates under mild conditions: A convenient access to 4-alkylidene-2-oxazolidinones
Ritter, Stefanie,Horino, Yoshikazu,Lex, Johann,Schmalz, Hans-Günther
, p. 3309 - 3313 (2008/09/18)
On treatment with catalytic amounts of gold(I) chloride (AuCl) and a base co-catalyst, O-propargyl carbamates smoothly undergo a 5-exo-dig cyclization at room temperature to afford 4-methylene-2-oxazolidinones in high yield. Substrates with a substituent
