929617-07-2Relevant academic research and scientific papers
Design, synthesis, and evaluation of efflux substrate-metal chelator conjugates as potential antimicrobial agents
Zhang, Yanling,Eric Ballard,Zheng, Shi-Long,Gao, Xingming,Ko, Ko-Chun,Yang, Hsiuchin,Brandt, Gary,Lou, Xinhui,Tai, Phang C.,Lu, Chung-Dar,Wang, Binghe
, p. 707 - 711 (2007)
Maintaining a proper balance of metal concentrations is critical to the survival of bacteria. We have designed and synthesized a series of conjugates of metal chelators and efflux transporter substrates aimed at disrupting bacterial metal homeostasis to a
