929617-80-1Relevant academic research and scientific papers
Benzothiazole benzimidazole (S)-isothiazolidinone derivatives as protein tyrosine phosphatase-1B inhibitors
Sparks, Richard B.,Polam, Padmaja,Zhu, Wenyu,Crawley, Matthew L.,Takvorian, Amy,McLaughlin, Erin,Wei, Min,Ala, Paul J.,Gonneville, Lucie,Taylor, Nancy,Li, Yanlong,Wynn, Richard,Burn, Timothy C.,Liu, Phillip C.C.,Combs, Andrew P.
, p. 736 - 740 (2007/10/03)
Benzothiazole benzimidazole (S)-isothiazolidinone ((S)-IZD) derivatives 5 were discovered through a peptidomimetic modification of the tripeptide (S)-IZD protein tyrosine phosphatase 1B (PTP1B) inhibitor 1. These derivatives are potent, competitive, and r
