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4-Thiazolidinone, 5-[[5-[(2-furanylmethyl)thio]-1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl] methylene]-2-thioxo- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

929634-45-7

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929634-45-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 929634-45-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,9,6,3 and 4 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 929634-45:
(8*9)+(7*2)+(6*9)+(5*6)+(4*3)+(3*4)+(2*4)+(1*5)=207
207 % 10 = 7
So 929634-45-7 is a valid CAS Registry Number.

929634-45-7Downstream Products

929634-45-7Relevant academic research and scientific papers

5-((1H-Pyrazol-4-yl)methylene)-2-thioxothiazolidin-4-one inhibitors of ADAMTS-5

Gilbert, Adam M.,Bursavich, Matthew G.,Lombardi, Sabrina,Georgiadis, Katy E.,Reifenberg, Erica,Flannery, Carl R.,Morris, Elisabeth A.

, p. 1189 - 1192 (2007/10/03)

A series of 5-((1H-pyrazol-4-yl)methylene)-2-thioxothiazolidin-4-one inhibitors of ADAMTS-5 (aggrecanase-2) is described. These compounds show μM functional inhibition of ADAMTS-5, and represent a new class of agents with the potential of inhibiting degradation of aggrecan, a major component of cartilage which is lost in osteoporosis. Compound 12 is noteworthy in that it has an ADAMTS-5 IC50: 1.1 μM and shows >40-fold functional selectivity over ADAMTS-4 (aggrecanase-1).

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