929693-08-3

Upstream product

• 256489-54-0 3-[(E)-(2R,3R)-2,4-dimethyl-5-iodo-3-hydroxypent-4-enoyl]-(R)-4-benzyloxazolidin-2-one 
• 929693-24-3 (2R,4S)-methyl 2-(3,4-dimethoxybenzyloxy)-4-(4-methoxybenzyloxy)hept-6-enoate 
• 929693-23-2 (2R,4S)-2-(3,4-dimethoxybenzyloxy)-4-(4-methoxybenzyloxy)hept-6-enoic acid 
• 929693-06-1 (2R,4S)-2-(3,4-dimethoxybenzyloxy)-4-(4-methoxybenzyloxy)hept-6-enal 
• 929693-22-1 (2R,4S)-2-(3,4-dimethoxybenzyloxy)-4-(4-methoxybenzyloxy)hept-6-en-1-ol 
• 929693-21-0 ((2R,4S)-2-(3,4-dimethoxybenzyloxy)-4-(4-methoxybenzyloxy)hept-6-enyloxy)triisopropylsilane 
• 929693-26-5 (2R,3S,4E,6S,7R,8E)-7-(tert-butyldimethylsilyloxy)-3-hydroxy-9-iodo-N-methoxy-N,2,6,8-tetramethylnona-4,8-dienamide 
• 929692-99-9 (2E,4S,5R,6E)-5-(tert-butyldimethylsilyloxy)-7-iodo-4,6-dimethylhepta-2,6-dienal 
• 123083-91-0 (2R,3R,E)-methyl 3-(tert-butylmethylsilyloxy)-5-iodo-2,4-dimethylpent-4-enoate 
• 123084-04-8 (2R,3R,E)-methyl 3-hydroxy-5-iodo-2,4-dimethylpent-4-enoate 
• 106484-92-8 (2R,3R,E)-3-(tert-butyldimethylsilyloxy)-5-iodo-2,4-dimethylpent-4-enal 

Downstream Products

• 929693-10-7 (2R,3S,4E,6S,7R,8E,10S,11R,13S)-3,7,10-tris(tert-butyldimethylsilyloxy)-11-(3,4-dimethoxybenzyloxy)-N-methoxy-13-(4-methoxybenzyloxy)-N,2,6,8-tetramethylhexadeca-4,8,15-trienamide 
• 929693-27-6 (2R,3S,4E,6S,7R,8E,10S,11R,13S)-3,7,10-tris(tert-butyldimethylsilyloxy)-11-hydroxy-N-methoxy-13-(4-methoxybenzyloxy)-N,2,6,8-tetramethylhexadeca-4,8,15-trienamide 
• 929693-29-8 (2R,3S,4E,6S,7R,8E,10S,11R,13S)-3,7,10,11-tetrakis(tert-butyldimethylsilyloxy)-N-methoxy-13-(4-methoxybenzyloxy)-N,2,6,8-tetramethylhexadeca-4,8,15-trienamide 
• 929693-11-8 (2R,3S,4E,6S,7R,8E,10S,11R,13S)-3,7,10,11-tetrakis(tert-butyldimethylsilyloxy)-13-(4-methoxybenzyloxy)-2,6,8-trimethylhexadeca-4,8,15-trienal 

Relevant academic research and scientific papers

Enantioselective synthesis of oasomycin A, part I: Synthesis of the C1-C12 and C13-C28 subunits

(Chemical Equation Presented) Putting the pieces together: The total synthesis of the natural macrolide oasomycin A has been realized. Key fragment couplings include an anti-Felkin selective aldol addition (green), Kociensky-Julia olefinations (red), and competitive Weinreb amide acylation reaction (blue). The utility of the 4,5-diphenyloxazole as a carboxy surrogate and the late-stage macrolactonization affording the 42-membered macrocycle of oasomycin A are also described.