92977-40-7Relevant academic research and scientific papers
Silver-catalyzed chemoselective annulation of propargyl amines with alkynes for access to pyridines and pyrroles
Nizami, Tauqir A.,Hua, Ruimao
, p. 6080 - 6084 (2017/09/23)
The annulation of propargyl amines with electron-deficient alkynes in the presence of silver salts affording pyridines and pyrroles has been developed. The chemoselective [4+2] or [3+2] annulation approach to pyridines or pyrroles depends on the structure
Synthesis of 1,2,3,5-tetrasubstituted pyrrole derivatives from 2-(2-bromoallyl)-1,3-dicarbonyl compounds
Demir, Ayhan S,Akhmedov, Idris M,Sesenoglu, ?zge
, p. 9793 - 9799 (2007/10/03)
2-(2-Bromoallyl)-1,3-dicarbonyl compounds are converted into β-enamino, β-hydrazino esters and ketones, followed by base-promoted cyclization, leading to the formation of the corresponding 1,2,3,5-tetrasubstituted pyrroles. 1,2,4- and 1,2,3,4-Substituted pyrroles are also isolated as minor products. Starting from the 2-(2-bromoallyl)-cyclohexane-1,3-dione the corresponding tetrahydro indolone is prepared in good yield.
