92990-85-7Relevant academic research and scientific papers
Concise Synthesis and Biological Evaluation of 2-Aroyl-5-Amino Benzo[ b ]thiophene Derivatives As a Novel Class of Potent Antimitotic Agents
Romagnoli, Romeo,Baraldi, Pier Giovanni,Lopez-Cara, Carlota,Preti, Delia,Aghazadeh Tabrizi, Mojgan,Balzarini, Jan,Bassetto, Marcella,Brancale, Andrea,Fu, Xian-Hua,Gao, Yang,Li, Jun,Zhang, Su-Zhan,Hamel, Ernest,Bortolozzi, Roberta,Basso, Giuseppe,Viola, Giampietro
, p. 9296 - 9309 (2014/01/06)
The biological importance of microtubules make them an interesting target for the synthesis of antitumor agents. The 2-(3′,4′,5′- trimethoxybenzoyl)-5-aminobenzo[b]thiophene moiety was identified as a novel scaffold for the preparation of potent inhibitor
Synthesis and evaluation of a thio analogue of duocarmycin SA
MacMillan, Karen S.,Lajiness, James P.,Cara, Carlota Lopez,Romagnoli, Romeo,Robertson, William M.,Hwang, Inkyu,Baraldi, Pier Giovanni,Boger, Dale L.
supporting information; experimental part, p. 6962 - 6965 (2010/06/16)
The design, synthesis, and preliminary evaluation of methyl 1,2,8,8a-tetrahydrocyclopropa[c]thieno[3,2-e]indol-4-one-6-carboxylate (CTI) derivatives are detailed representing a single atom change (N to S) embedded in the duocarmycin SA alkylation subunit.
PHOTOCHROMISM. SYNTHESIS AND PROPERTIES OF INDOLINOSPIROBENZOTHIOPYRANS
Arakawa, Sei'ichi,Kondo, Hirofumi,Seto, Jun'etsu
, p. 1805 - 1808 (2007/10/02)
Novel photochromic compounds, indolinospirobenzothiopyrans, were prepared and their properties in polymer films were examined.The absorption bands of the colored form lie around 100 nm deeper in the long-wave region of the spectrum than are the case with the common spiropyrans.
