930-63-2

Usage

Uses

Used in Pharmaceutical Industry:
3-Methyl-1,2,4-triazol-5-one is used as a key intermediate for the synthesis of various pharmaceuticals due to its biological activities, which include anti-inflammatory and antifungal properties. Its molecular structure allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 3-Methyl-1,2,4-triazol-5-one is utilized as a building block for the creation of herbicidal compounds. Its herbicidal properties make it a valuable component in the production of agricultural chemicals aimed at controlling weed growth, thereby enhancing crop yields.
Used in Organic Synthesis:
3-Methyl-1,2,4-triazol-5-one is employed as a versatile intermediate in organic synthesis, facilitating the construction of complex organic molecules for a wide range of applications in medicinal and agricultural chemistry. Its unique structure and reactivity contribute to the development of innovative chemical entities with diverse functionalities.

InChI:InChI=1/C3H5N3O/c1-2-4-3(7)6-5-2/h1H3,(H2,4,5,6,7)

Upstream product

• 52838-39-8 5-methyl-[1,3,4]oxadiazol-2-ylamine 
• 2302-87-6 2-acetylhydrazinecarboxamide 
• 116340-25-1 trimethylsilyl methyl-3-triazole-1,2,4-one-5 
• 1445-45-0 Trimethyl orthoacetate 
• 4426-72-6 hydrazine carboxamide 
• 84690-54-0 N,N-dimethylamino-N'-ethoxycarbonylacetamidine 

Downstream Products

• 251451-27-1 4-Hydroxymethyl-3-methyl-1,2,4-triazol-5-one 
• 1095279-89-2 3-[6-Bromo-2-fluoro-3-(3-methyl-5-oxo-1,5-dihydro-[1,2,4]triazol4-ylmethyl)-phenoxy]-5-chloro-benzonitrile 
• 98292-40-1 4-(2,3,5-Tri-O-benzoyl-β-D-ribofuranosyl)-5-methyl-1,2,4-triazol-3(2H)-one 
• 98292-38-7 2,4-dibenzyl-5-methyl-1,2,4-triazol-3(2H)-one 
• 90840-19-0 4-Benzyl-5-methyl-1,2,4-triazol-3(2H)-one 

Relevant academic research and scientific papers

Non-Nucleoside reverse transcriptase inhibitors

Compounds of formula I, wherein R1, R2, R3, X and Ar, are as defined herein or pharmaceutically acceptable salts thereof, inhibit HIV-1 reverse transcriptase and afford a method for prevention and treatment of HIV-1 infections and the treatment of AIDS and/or ARC. The present invention also relates to compositions containing compounds of formula I useful for the prevention and treatment of HIV-1 infections and the treatment of AIDS and/or ARC.

DISILYLATED COMPOUNDS AS PRECURSORS OF HETEROCYCLES: SYNTHESIS OF BENZIMIDAZOLES, TRIAZOLES, FURAN AND PYRROLE.

The cyclization of disilylated compounds catalyzed by trifluoromethanesulfonoc acid is an easy way to obtain some heterocycles such as benzimidazole, triazole, furan and pyrrole.

ACETALS OF LACTAMS AND ACID AMIDES. 37. * REACTIONS OF AMIDE AND LACTAM ACETALS WITH DERIVATIVES OF UREA AND URETHANE AND SYNTHESIS OF CONDENSED PYRIMIDINES

The reactions of diethylacetals of dimethylacetamide and N-methylbutyro-, -valero-, and -caprolactams with urea, thiourea, and urethane lead to the corresponding N-carbamide- and N-ethoxycarbonylamides, on the basis of which derivatives of pyrimidine and pyrrolo- and pyridopyrimidine and pyridoazepine, as well as triazole derivatives, were synthetized.