930285-75-9Relevant academic research and scientific papers
Synthesis of the core structure of cruentaren A
Vintonyak, Viktor V.,Maier, Martin E.
, p. 655 - 658 (2008/02/05)
The core structure of the macrolactone cruentaren A (1) was prepared via a ring-closing alkyne metathesis reaction. The corresponding ester 33 was constructed from the benzoic acid derivative 14 and the diol 30. As a key step in the synthesis of acid 14, an aldol reaction resulted in the required anti-OH/Me pattern. The anti-configuration in the stereotetrad of diol 30 was established by a Marshall reaction.
