930286-84-3Relevant academic research and scientific papers
NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS
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, (2016/04/19)
In its many embodiments, the present invention provides a class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases (CDKs), methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds
Discovery of pyrazolo[1,5-a]pyrimidine-based CHK1 inhibitors: A template-based approach - Part 2
Labroli, Marc,Paruch, Kamil,Dwyer, Michael P.,Alvarez, Carmen,Keertikar, Kartik,Poker, Cory,Rossman, Randall,Duca, Jose S.,Fischmann, Thierry O.,Madison, Vincent,Parry, David,Davis, Nicole,Seghezzi, Wolfgang,Wiswell, Derek,Guzi, Timothy J.
scheme or table, p. 467 - 470 (2011/02/27)
Previous efforts by our group have established pyrazolo[1,5-a]pyrimidine as a viable core for the development of potent and selective CDK inhibitors. As part of an effort to utilize the pyrazolo[1,5-a]pyrimidine core as a template for the design and synth
