930294-01-2

Upstream product

• 16473-35-1 4-(hydroxymethyl)benzyl chloride 
• 866268-32-8 2-butoxy-8-methoxy-9H-purine-6-amine trifluoroacetic acid 
• 866268-29-3 8-bromo-2-butoxy-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine 

Downstream Products

• 930785-12-9 2-Butoxy-7,8-dihydro-9-{4-[N-(3-hydroxypropyl)aminomethyl]-benzyl}-8-oxoadenine 
• 930293-62-2 C₂₄H₃₂N₆O₄ 
• 930293-56-4 2-butoxy-7,8-dihydro-9-[4-(N-ethoxycarbonylmethyl-N-methylamino)methylbenzyl]-8-oxoadenine 

Relevant academic research and scientific papers

ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF

Disclosed herein are TLR-agonists compounds, antibody-TLR agonist conjugates, pharmaceutical composition, and methods of use of such compounds or conjugates as therapeutics for treating a disease or condition such as cancer.

COMPOSITIONS CONTAINING, METHODS AND USES OF ANTIBODY-TLR AGONIST CONJUGATES

Disclosed herein are Trastuzumab-linked TLR-agonist derivative analogs that include at least one non-natural amino acid, and methods for making such non-natural amino acids and polypeptides. The Trastuzumab-linked TLR-agonist derivative analogs can includ