930300-69-9Relevant academic research and scientific papers
Development of new pyrrolopyrimidine-based inhibitors of Janus kinase 3 (JAK3)
Clark, Michael P.,George, Kelly M.,Bookland, Roger G.,Chen, Jack,Laughlin, Steven K.,Thakur, Kumar D.,Lee, Wenlin,Davis, Jan R.,Cabrera, Ed J.,Brugel, Todd A.,VanRens, John C.,Laufersweiler, Matthew J.,Maier, Jennifer A.,Sabat, Mark P.,Golebiowski, Adam,Easwaran, Vijay,Webster, Mark E.,De, Biswanath,Zhang, George
, p. 1250 - 1253 (2007/10/03)
A new class of bicyclic pyrrolopyrimidine-based Janus kinase 3 (JAK-3) inhibitors are described. Many of these inhibitors showed low nanomolar activity against JAK-3.
