930576-16-2

Upstream product

• 930576-15-1 1-(4-fluorophenyl)-3-nitropyridin-2(1H)-one 
• 6332-56-5 2-hydroxy-3-nitropyridine 
• 1765-93-1 4-fluoroboronic acid 

Downstream Products

• 930576-24-2 4-(2-fluoro-4-((1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridin-3-yl)carbamoyl)phenoxy)picolinamide 
• 930576-17-3 2,4,5-trifluoro-N-(1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridin-3-yl)benzamide 

Relevant academic research and scientific papers

IMIDAZOPYRIDAZINE COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFN ALPHA RESPONSES

Compounds having the following formula (I), or a stereoisomer or pharmaceutically-acceptable salt thereof, where R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNα, by acting on Tyk-2 to cause signal transduction inhibition.

Fused heterocyclic compounds useful as kinase modulators

Compounds having the formula (1), and enantiomers, and diastereomers, pharmaceutically-acceptable salts, thereof, are usefuil as kinase modulators, including MK2 modulation, wherein one of E and F is a nitrogen atom and the other of E and F is a carbon atom, Z is N or CR3, and R1, R2, R3, X and Y are as defined herein.