930579-56-9Relevant academic research and scientific papers
Synthesis of (Z)-alkene-containing cis-proline dipeptide mimetics using samarium(II) diiodide (SmI2)-mediated reductive alkylation reaction
Sasaki, Yoshikazu,Shigenaga, Akira,Fujii, Nobutaka,Otaka, Akira
, p. 2000 - 2008 (2007/10/03)
The amide bond between an amino acid and proline can take the trans- or cis-conformation. The conformation influences both the structure and function of peptides and proteins. Therefore, constrained mimetic, which corresponds to Pro-dipeptides whose amide
