930604-02-7

Upstream product

• 109-01-3 1-methyl-piperazine 
• 6094-60-6 1-benzyl-4-hydroxypiperidine-4-carbonitrile 
• 3612-20-2 1-phenylmethyl-4-piperidone 

Downstream Products

• 930604-03-8 1-(1-benzyl-4-methyl-piperidin-4-yl)-4-methyl-piperazine 
• 891662-36-5 C₁₈H₃₀N₄ 
• 1186240-86-7 N-((1-(2-(2-(4-methoxy-N,2,6-trimethylphenylsulfonamido)ethoxy)acetyl)-4-(4-methylpiperazin-1-yl)piperidin-4-yl)methyl)isonicotinamide hydrochloride 
• 1186240-87-8 N-((1-(2-((4-(4-methoxy-2,6-dimethylphenylsulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-3-yl)methoxy)acetyl)-4-(4-methylpiperazin-1-yl)piperidin-4-yl)methyl)isonicotinamide 
• 1186240-25-4 N-((1-(2-(2-(4-methoxy-N,2,6-trimethylphenylsulfonamido)ethoxy)acetyl)-4-(4-methylpiperazin-1-yl)piperidin-4-yl)methyl)isonicotinamide 
• 1186241-24-6 C₃₀H₅₁N₅O₇S 
• 1186241-30-4 N-(2-(2-(4-(aminomethyl)-4-(4-methylpiperazin-1-yl)piperidin-1-yl)-2-oxoethoxy)ethyl)-4-methoxy-N,2,6-trimethylbenzensulfonamide 
• 1186241-46-2 C₂₀H₂₉F₃N₄O 
• 1186241-12-2 C₂₄H₃₃N₅O 
• 1186241-22-4 C₂₃H₃₈N₄O₂ 

Relevant academic research and scientific papers

Substituted Indole Compounds

Substituted indole compounds corresponding to the formula I: In which R8, R9a, R9b, R10, R11, R200, R210, A, D, T, q, s and t have defined meanings, processes for the preparation thereof, pharmaceutical compositions containing such compounds and the use of substituted indole compounds for the treatment or inhibition of pain and other conditions which are at least partly mediated by Bradykinin 1 receptors (B1R).

SUBSTITUTED SULFONAMIDE DERIVATIVES

The invention relates to substituted sulfonamide derivatives, processes for the preparation thereof, medicaments containing these compounds and the use of substituted sulfonamide derivatives for the preparation of medicaments.

Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions

The present invention relates to the CGRP-antagonists of general formula I wherein R1, R2, R3 and R4 are defined as in claim 1, the tautomers, the isomers, the diastereomers, the enantiomers, the hydrates thereof, the mixtures thereof and the salts thereof and the hydrates of the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, as well as those compounds of general formula I wherein one or more hydrogen atoms are replaced by deuterium, pharmaceutical compositions containing these compounds, their use and processes for preparing them.