93071-78-4 Usage
Uses
Used in Pharmaceutical Industry:
CHEMBRDG-BB 4002912 is used as a potential cholesterol-lowering agent for the development of new medications. It targets the HMG-CoA reductase enzyme, which is essential in cholesterol synthesis, offering a therapeutic approach to managing high cholesterol levels in the blood.
Additionally, as its exact pharmacological and biological properties are still under investigation, CHEMBRDG-BB 4002912 may also have potential applications in other therapeutic areas, expanding its use in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 93071-78-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,3,0,7 and 1 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 93071-78:
(7*9)+(6*3)+(5*0)+(4*7)+(3*1)+(2*7)+(1*8)=134
134 % 10 = 4
So 93071-78-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H11NS/c1-10-8-4-2-3-7(5-8)6-9/h2-5H,6,9H2,1H3
93071-78-4Relevant academic research and scientific papers
Analysis of structure-activity relationships for the 'A-region' of N-(4-t-butylbenzyl)-N′-[4-(methylsulfonylamino)benzyl]thiourea analogues as TRPV1 antagonists
Lee, Jeewoo,Kang, Sang-Uk,Kil, Min-Jung,Shin, Myoungyoup,Lim, Ju-Ok,Choi, Hyun-Kyung,Jin, Mi-Kyoung,Kim, Su Yeon,Kim, Sung-Eun,Lee, Yong-Sil,Min, Kyung-Hoon,Kim, Young-Ho,Ha, Hee-Jin,Tran, Richard,Welter, Jacqueline D.,Wang, Yun,Szabo, Tamas,Pearce, Larry V.,Lundberg, Daniel J.,Toth, Attila,Pavlyukovets, Vladimir A.,Morgan, Matthew A.,Blumberg, Peter M.
, p. 4136 - 4142 (2007/10/03)
The structure-activity relationships for the 'A-region' of N-(4-t-butylbenzyl)-N′-[4-(methylsulfonylamino)benzyl]thiourea analogues have been investigated as TRPV1 receptor antagonists. The 2-halogen analogues showed enhanced antagonism compared to the prototype antagonist.
