930784-54-6

Basic information

• Product Name: (1R)-2,2',3,3'-tetrahydro-6,6'-dimethyl-1,1'-Spirobi[1H-indene]-7,7'-diol
• Synonyms: (R)-2,2',3,3'-Tetrahydro-6,6'-dimethyl-1,1'-spirobi[1H-indene]-7,7'-diol,99%e.e.;(R)-2,2',3,3'-Tetrahydro-6,6'-dimethyl-1,1'-spirobi[1H-indene]-7,7'-diol
• CAS NO: 930784-54-6
• Molecular Formula: C19H20O2
• Molecular Weight: 280.3609
• Mol File: 930784-54-6.mol
• Article Data: 1

Chemical Properties

• Melting Point: 105-106 °C
• Boiling Point: 435.9±45.0 °C(Predicted)
• Appearance: /
• Density: 1.27±0.1 g/cm3(Predicted)
• PKA: 10.01±0.20(Predicted)
• CAS DataBase Reference: (1R)-2,2',3,3'-tetrahydro-6,6'-dimethyl-1,1'-Spirobi[1H-indene]-7,7'-diol(CAS DataBase Reference)
• NIST Chemistry Reference: (1R)-2,2',3,3'-tetrahydro-6,6'-dimethyl-1,1'-Spirobi[1H-indene]-7,7'-diol(930784-54-6)
• EPA Substance Registry System: (1R)-2,2',3,3'-tetrahydro-6,6'-dimethyl-1,1'-Spirobi[1H-indene]-7,7'-diol(930784-54-6)

Safety Data

• Hazardous Substances Data: 930784-54-6(Hazardous Substances Data)

Usage

Description

(1R)-2,2',3,3'-tetrahydro-6,6'-dimethyl-1,1'-Spirobi[1H-indene]-7,7'-diol, also known as TMB, is a synthetic spirocyclic compound with potential pharmaceutical applications. It has a unique structure and has been studied for its potential use in treating neurological disorders and as an antioxidant. TMB has demonstrated neuroprotective effects in certain experimental models and has been investigated for its potential role in reducing oxidative stress in the body. Research into the potential uses and applications of TMB is ongoing, and it may hold promise for future therapeutic interventions.

Uses

Used in Pharmaceutical Industry:
TMB is used as a potential therapeutic agent for neurological disorders due to its neuroprotective effects observed in experimental models. Its unique structure and potential antioxidant properties make it a promising candidate for further research and development in this field.
Used in Antioxidant Applications:
TMB is used as a potential antioxidant to reduce oxidative stress in the body. Its ability to combat oxidative stress may contribute to its potential therapeutic effects in various conditions and diseases.

Downstream Products

• 930784-57-9 N-dimethyl-[(R)-6,6'-dimethyl-1,1'-spirobiindane-7,7'-diyl]-phosphoramidite 

Relevant articles and documents

Asymmetric reductive coupling of dienes and aldehydes catalyzed by nickel complexes of spiro phosphoramidites: Highly enantioselective synthesis of chiral bishomoallylic alcohols

A highly efficient nickel-catalyzed asymmetric reductive coupling of dienes and aldehydes has been realized by using bulky spirobiindane phosphoramidite ligands, affording bishomoallylic alcohols in high yields with excellent diastereoselectivities and en