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Usage

Uses

Used in Organic Synthesis:
(1R)-2,2',3,3'-tetrahydro-6,6'-diphenyl-1,1'-Spirobi[1H-indene]-7,7'-diol is used as a key intermediate for the synthesis of complex organic molecules, leveraging its unique spiro structure and chiral center to facilitate the formation of novel compounds.
Used in Materials Science:
In the materials science industry, (1R)-2,2',3,3'-tetrahydro-6,6'-diphenyl-1,1'-Spirobi[1H-indene]-7,7'-diol is used as a building block for the development of new materials, such as polymers and composites, due to its structural rigidity and potential for self-assembly.
Used in Pharmaceutical Research:
(1R)-2,2',3,3'-tetrahydro-6,6'-diphenyl-1,1'-Spirobi[1H-indene]-7,7'-diol is utilized as a lead compound in drug discovery, with its chirality and steric hindrance from diphenyl groups offering opportunities for the design of new pharmaceutical agents with improved selectivity and potency.
Further research and exploration of (1R)-2,2',3,3'-tetrahydro-6,6'-diphenyl-1,1'-Spirobi[1H-indene]-7,7'-diol could lead to the development of innovative materials and drug candidates, highlighting its potential across various scientific disciplines.

Upstream product

• 1621066-74-7 (R)-6,6'-dibromo-2,2',3,3'-tetrahydro-1,1'-spirobis[1H-indole]-7,7'-diphenol 
• 98-80-6 phenylboronic acid 

Relevant academic research and scientific papers

Optically active 1,1′-Spirobiindane-7,7′-diol (SPINOL)-based phosphoric acids as highly enantioselective catalysts for asymmetric organocatalysis

The synthesis and application of a series of optically active 1,1′-spirobiindane-7,7′-diol (SPINOL)-based phosphoric acids are described. These SPINOL-based phosphoric acids were prepared from (R)-SPINOL in three steps and exhibited excellent enantioselec

SPINOL-derived phosphoric acids: Synthesis and application in enantioselective Friedel-Crafts reaction of indoles with imines

A new class of chiral phosphoric acids with spirobiindane as scaffold were conveniently synthesized from (S)-1,1′-spirobiindane-7,7′-diol ((S)-SPINOL) and employed to catalyze the asymmetric Friedel-Crafts reaction of indoles with imines to afford 3-indol

Asymmetric reductive coupling of dienes and aldehydes catalyzed by nickel complexes of spiro phosphoramidites: Highly enantioselective synthesis of chiral bishomoallylic alcohols

A highly efficient nickel-catalyzed asymmetric reductive coupling of dienes and aldehydes has been realized by using bulky spirobiindane phosphoramidite ligands, affording bishomoallylic alcohols in high yields with excellent diastereoselectivities and en