930797-61-8Relevant academic research and scientific papers
SULFONANILIDE ANALOGS AS SELECTIVE AROMATASE MODULATORS
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Page/Page column 34; 4/15; 12/15, (2010/11/28)
Compounds and methods suppressing aromatase activity expression in cancer cells. Provided are compounds are those of formula I: wherein R1 may be alkyl, cycloakyl, haloalkyl, aryl, substituted aryl, haloaryl, alkoxy, alkylaryl, and arylalkyl; R2 is H, alk
Synthesis and biological evaluation of selective aromatase expression regulators in breast cancer cells
Su, Bin,Landini, Serena,Davis, Danyetta D.,Brueggemeier, Robert W.
, p. 1635 - 1644 (2007/10/03)
Aromatase converts androgens to estrogens and is a particularly attractive target in the treatment of estrogen receptor positive breast cancer. The enzyme is encoded by the CYP19 gene, which is expressed in a tissue-specific manner. Prostaglandin E2
