930798-25-7

Usage

Uses

Used in Pharmaceutical Industry:
(6-Chloropyrazin-2-yl)acetic acid is used as an intermediate in the synthesis of various pharmaceuticals for its potential to contribute to the development of new drugs. Its unique structure allows it to be a building block in the creation of compounds with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, (6-Chloropyrazin-2-yl)acetic acid is utilized as an intermediate in the production of agrochemicals. Its role in this industry is to help develop compounds that can be used in agriculture to protect crops and enhance their growth, thereby contributing to increased agricultural productivity.

InChI:InChI=1/C6H5ClN2O2/c7-5-3-8-2-4(9-5)1-6(10)11/h2-3H,1H2,(H,10,11)

Upstream product

• 930798-26-8 2-(6-chloro-pyrazin-2-yl)-malonic acid diethyl ester 

Downstream Products

• 5521-56-2 6-methylpyrazin-2-amine 
• 1079362-68-7 (4-chloro-phenyl)-(6-methyl-pyrazin-2-yl)-amine 
• 1079362-67-6 (6-methyl-pyrazin-2-yl)-phenylamine 
• 1648864-49-6 ethyl-2-(2-chloro-4-(6-methylpyrazin-2-yl)phenyl)acetate 

Relevant academic research and scientific papers

ANTIDIABETIC BICYCLIC COMPOUNDS

Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-co

SERINE/THREONINE KINASE INHIBITORS

Compounds having the formula I wherein R1, R2, R3, R4, R5, Ra, Rb, Rc, Rd, Re, n, r, s and t are as defined herein and which compounds are inhibitors of PAK1. Also disclosed are compositions and methods for treating cancer and hyperproliferative disorders.

A general and efficient route to 6-methyl-pyrazin-2-yl-amines: Alkylation of 2,6-dichloropyrazine via malonate derivatives

(Chemical Equation Presented) We have developed a convenient two-stage process for the synthesis of 6-methylpyrazine-2-yl-amines from commercially available materials. The procedure involves the synthesis of (6-chloro-pyrazin-2-yl)-acetic acid via arylati

NOVEL PROCESS FOR THE PREPARATION OF 6-METHYL-PYRAZIN-2-YLAMINE

A new process for the preparation of 6-methyl-pyrazin-2- ylamine is described. The process involves reacting 2,6- dichloropyrazine with a dialkylmalonate followed by subsequent decarboxylation rendering a new compound, 6-chloro-pyrazin-2- yl -'acetic acid. Further decarboxylation and amination renders the desired product.

NOVEL N-PYRAZINIL-PHENYLSULFONAMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF ASTHMA

The invention provides a compound of formula (I), wherein R1, R2 and R3 are as defined in the specification, pharmaceutical compositions containing them, a process for preparing the pharmaceutical compositions, and their use in therapy.