93080-10-5

Basic information

• Product Name: Thiophene, 3-(1,2-diphenylethenyl)-
• CAS NO: 93080-10-5
• Molecular Formula: C18H14S
• Molecular Weight: 262.375
• Mol File: 93080-10-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Thiophene, 3-(1,2-diphenylethenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Thiophene, 3-(1,2-diphenylethenyl)-(93080-10-5)
• EPA Substance Registry System: Thiophene, 3-(1,2-diphenylethenyl)-(93080-10-5)

Safety Data

• Hazardous Substances Data: 93080-10-5(Hazardous Substances Data)

Upstream product

• 10486-61-0 3-thienyl iodide 
• 501-65-5 diphenyl acetylene 
• 527-72-0 2-thiophenylcarboxylic acid 

Relevant articles and documents

Regioselective C-H Hydroarylation of Internal Alkynes with Arenecarboxylates: Carboxylates as Deciduous Directing Groups

In the presence of catalytic [Ru(p-cym)I2]2and the base guanidine carbonate, benzoic acids react with internal alkynes to give the corresponding 2-vinylbenzoic acids. This alkyne hydroarylation is generally applicable to diversely substituted electron-rich and electron-poor benzoic and acrylic acids. Aryl(alkyl)acetylenes react regioselectively with formation of the alkyl-branched hydroarylation products, and propargylic alcohols are converted into γ-alkylidene-δ-lactones. The hydroarylation can also be conducted decarboxylatively with a different choice of catalyst and reaction conditions. This reaction variant, which does not proceed via intermediate formation of 2-vinylbenzoic acids, opens up a regioselective, waste-minimized synthetic entry to vinylarenes. Make the switch: A simple ruthenium(II) complex catalyzes the regioselective hydroarylation of internal alkynes with benzoic acids. The conditions can be tuned to switch from a non-decarboxylative to a decarboxylative pathway. Aryl(alkyl)acetylenes react regioselectively with formation of the alkyl-branched 2-vinylbenzoic acids, and propargylic alcohols cyclize to γ-alkylidene-δ-lactones.