930806-12-5Relevant academic research and scientific papers
Spacer-separated sialyl LewisX cyclopeptide conjugates as potential E-selectin ligands
Herzner, Holger,Kunz, Horst
, p. 541 - 557 (2007)
Completely protected sialyl LewisX azide was synthesized from a neolactosamine azide precursor carrying a 3-O-allyloxycarbonyl group as the temporary protecting group. After its Pd(0)-catalyzed deprotection and stereoselective α-fucosylation, the obtained
Synthetic glycopeptides from the E-selectin ligand 1 with varied sialyl Lewisx structure as cell-adhesion inhibitors of E-selectin
Filser, Christian,Kowalczyk, Danuta,Jones, Claire,Wild, Martin K.,Ipe, Ute,Vestweber, Dietmar,Kunz, Horst
, p. 2108 - 2111 (2008/03/12)
(Chemical Equation Presented) Cooperation is key: Peptide and saccharide portions cooperate in sialyl Lewisx glycopeptides and their mimetics in the fucose and sialic acid parts (see formula), resulting in up to greater than 100-fold stronger b
