93135-75-2Relevant academic research and scientific papers
Acyl migration from N6 to N7 of a 2',3'-O-isopropylideneadenosine derivative accompained by cyclonucleoside formation
Anzai, Kentaro,Uzawa, Jun
, p. 2109 - 2114 (2007/10/02)
Reaction of 2',3'-O-isopropylideneadenosine (1) with p-NCC6H4COCl in 1:6 Et3N-CH2Cl2 afforded the cyanoimidazole nucleoside 8 (53percent) and the 8,5'-O-cycloadenosine derivative 7 (29percent).Treatment of N6,N6-di-p-toluyl-2',3'-O-isopropilideneadenosine (23) with ZnBr2 in p-dioxane resulted in acyl migration from N6 to N7 to give the cycloadenosine derivative 4.The coordination site of the zinc cation on the base moiety of adenosine derivatives was determined by 15N nmr spectra.
Cyclonucleoside Formation and Ring Cleavage in the Reaction of 2',3'-O-Isopropylideneadenosine with Benzoyl Chloride and Its Substituted Derivatives
Anzai, Kentaro,Uzawa,Jun
, p. 5076 - 5080 (2007/10/02)
Reaction conditions suitable for the formation of 8,5'-O-cycloadenosine derivatives in the reaction of 2',3'-O-isopropylideneadenosine (1) with benzoyl chloride and substituted benzoyl chlorides were investigated.Thus, reaction of 1 with p-toluyl chloride
