93159-88-7 Usage
Uses
Used in Pharmaceutical Industry:
11,12-Dimethoxydihydrokawain is used as a natural anxiolytic agent for managing anxiety and stress. Its ability to modulate GABA receptors in the brain makes it a potential alternative to synthetic anxiety medications.
Used in Sleep Aid Products:
11,12-Dimethoxydihydrokawain is used as a natural sleep aid for treating insomnia and promoting restful sleep. Its calming effects on the brain can help alleviate sleep disturbances caused by stress and anxiety.
Used in Relaxation and Stress Relief Products:
11,12-Dimethoxydihydrokawain is used as a relaxation and stress relief agent in various products, such as supplements, teas, and topical applications. Its calming effects can help reduce muscle tension and alleviate stress-related disorders.
Used in Neurological Disorders Research:
11,12-Dimethoxydihydrokawain is used as a research compound for studying its potential therapeutic effects on neurological disorders, such as epilepsy and neuropathic pain. Its interaction with GABA receptors suggests that it may have potential in managing these conditions.
Used in Traditional Medicine:
11,12-Dimethoxydihydrokawain is used in traditional medicine practices, particularly in the Pacific Islands, for its sedative and anxiolytic properties. It is often consumed as a beverage made from the kava plant to promote relaxation and well-being.
Check Digit Verification of cas no
The CAS Registry Mumber 93159-88-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,3,1,5 and 9 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 93159-88:
(7*9)+(6*3)+(5*1)+(4*5)+(3*9)+(2*8)+(1*8)=157
157 % 10 = 7
So 93159-88-7 is a valid CAS Registry Number.
93159-88-7Relevant academic research and scientific papers
In vivo Structure-Activity Relationship of Dihydromethysticin in Reducing Nicotine-Derived Nitrosamine Ketone (NNK)-Induced Lung DNA Damage against Lung Carcinogenesis in A/J Mice
Hati, Santanu,Hu, Qi,Huo, Zhiguang,Lu, Junxuan,Xing, Chengguo
, (2022/03/08)
Lung cancer is the leading cause of cancer-related deaths and chemoprevention should be developed. We recently identified dihydromethysticin (DHM) as a promising candidate to prevent NNK-induced lung tumorigenesis. To probe its mechanisms and facilitate its future translation, we investigated the structure-activity relationship of DHM on NNK-induced DNA damage in A/J mice. Twenty DHM analogs were designed and synthesized. Their activity in reducing NNK-induced DNA damage in the target lung tissues was evaluated. The unnatural enantiomer of DHM was identified to be more potent than the natural enantiomer. The methylenedioxy functional moiety did not tolerate modifications while the other functional groups (the lactone ring and the ethyl linker) accommodated various modifications. Importantly, analogs of high structural similarity to DHM with distinct efficacy in reducing NNK-induced DNA damage have been identified. They will serve as chemical probes to elucidate the mechanisms of DHM in blocking NNK-induced lung carcinogenesis.
