93178-58-6

Upstream product

• 274-47-5 imidazo[1,5-a]pyridine 
• 1060812-82-9 5-iodoimidazo[1,5-a]pyridine 
• 4334-88-7 p-ethoxycarbonylphenylboronic acid 
• 102676-39-1 6-cyano-2-<4-(ethoxycarbonyl)phenyl>pyridine 
• 102676-40-4 6-(aminomethyl)-2-<4-(ethoxycarbonyl)phenyl>pyridine 
• 102676-38-0 2-<4-(ethoxycarbonyl)phenyl>pyridine N-oxide 
• 4385-61-9 ethyl 4-(2-pyridinyl)benzoate 
• 102676-41-5 2-<4-(ethoxycarbonyl)phenyl>-6-<(formylamino)methyl>pyridine 

Downstream Products

• 102676-47-1 fadrozole 
• 102676-43-7 5-(4-carbamylphenyl)-5,6,7,8-tetrahydroimidazo<1,5-a>pyridine 
• 93178-73-5 5-(4-carboxyphenyl)-5,6,7,8-tetrahydroimidazo<1,5-a>pyridine 
• 93178-72-4 5-<4-(ethoxycarbonyl)phenyl>-5,6,7,8-tetrahydroimidazo<1,5-a>pyridine hydrochloride 

Relevant academic research and scientific papers

Selective C(8)-H Activation of Imidazopyridines Mediated by Cooperative Nickel-Aluminum Catalysis

A catalytic paradigm is described featuring a synergistic interaction between nickel, aluminum and different ligands to impart a rather remote C-H alkenylation of imidazo[1,5-a]pyridines at the C-8 position without the necessity of installing a directing group. The scope of the direct C-H activation reactions of various 5-aryl- and 3-arylimidazopyridines is established using different sterically hindered alkynes.

Fedrazole Hydrochloride: A Potent, Selective, Nonsteroidal Inhibitor ofAromatase for the Treatment of Estrogen-Dependent Disease

A new class of potent, selective, nonsteroidal inhibitors of aromatase have been discovered.The most potent member of this series is fadrozole hydrochloride, CGS 16949 A, 4-(5,6,7,8-tetrahydroimidazopyridin-5-yl)benzonitrile monohydrochloride, 26a.