93185-76-3Relevant academic research and scientific papers
Synthesis of Indoles via Ring Closure of 2-Alkylnitroaniline Derivatives.
Bergman, Jan,Sand, Peter
, p. 6085 - 6112 (2007/10/02)
A variety of nitroindoles have been prepared from imidate, amidine, and sec-anilide derivatives of 2-alkyl-3- or 5-nitroanilines by a base-induced cyclization promoted by dialkyl oxalates.It is shown that essentially the same procedure also can be used to synthesize the corresponding nitroindole-3-glyoxylates in one simple operation.The synthetic potential is discussed and a mechanism is proposed.
