932020-02-5Relevant articles and documents
A short and efficient synthesis of 5-hydroxymethylcyclopent-2-enol from d-glucose and its elaboration to the carbanucleoside (-)-carbovir
Roy, Biswajit G.,Jana, Prithwish K.,Achari, Basudeb,Mandal, Sukhendu B.
, p. 1563 - 1566 (2007)
Introduction of an allyl functionality at C-3 of 1,2:5,6-di-O-isopropylidene-α-d-glucofuranose followed by olefination at C-5 and C-6 provided 1,6-diene 5 which, upon ring closing metathesis and subsequent functional group manipulation, furnished the key cyclopentene diacetate 7, which was elaborated to carbanucleoside (-)-carbovir 1.