93206-03-2Relevant academic research and scientific papers
Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 Inhibitors
Park, Hye-Kyung,Jeong, Hanbin,Ko, Eunhwa,Lee, Geumwoo,Lee, Ji-Eun,Lee, Sang Kwang,Lee, An-Jung,Im, Jin Young,Hu, Sung,Kim, Seong Heon,Lee, Ji Hoon,Lee, Changwook,Kang, Soosung,Kang, Byoung Heon
, p. 7569 - 7578 (2017)
Although Hsp90 inhibitors can inhibit multiple tumorigenic pathways in cancer cells, their anticancer activity has been disappointingly modest. However, by forcing Hsp90 inhibitors into the mitochondria with mitochondrial delivery vehicles, they were conv
NOVEL IMIDAZOTRIAZINONE OR IMIDAZOPYRAZINONE DERIVATIVES, AND USE THEREOF
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Paragraph 212; 217; 218, (2016/04/26)
The present invention relates to novel a imidazotriazinone or imidazopyrazinone derivative, a tautomer thereof, a stereoisomer thereof and their mixture, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating a tankyrase-related disease, which contains the same as an active ingredient.
Novel imidazotriazinone or imidazopyrazinone derivatives, and use thereof
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, (2016/10/07)
The present invention relates to a novel imidazotriazinone or imidazopyrazinone derivatives, a tautomer thereof, a stereomer and a mixture thereof, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating tankyrase-related diseases comprising the same as active components.COPYRIGHT KIPO 2016
PROCESS FOR SUBSTITUTED 3-AMINO-5-OXO-4,5-DIHYDRO-[1,2,4]TRIAZINES
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Page/Page column 8, (2011/02/24)
Processes including preparation of trans-4-[(3-amino-5-oxo-4,5-dihydro-[1,2,4]triazin-6-ylmethyl)-carbamoyl]-cyclohexanecarboxylic acid methyl ester, and its conversion to trans-4-(4-amino-5-susbtituted-imidazo[5,1-?][1,2,4]triazin-7-yl)-cyclohexanecarbox
