93249-31-1

Upstream product

• 51321-61-0 2-bromo-N,N-diisopropylacetamide 
• 873-55-2 sodium benzenesulfonate 
• 1360789-21-4 2-(phenylsulfonyl)-1-(2,2,6,6-tetramethylpiperidin-1-yl)ethanone 
• 3959-23-7 benzenesulfonylacetic acid 
• 108-18-9 diisopropylamine 
• 61698-72-4 N,N-diisopropyl-2-(phenylsulfanyl)acetamide 
• 128100-22-1 Benzenesulfonyl-acetic acid (2S,3S)-3-phenyl-oxiranylmethyl ester 
• 4111-54-0 lithium diisopropyl amide 

Downstream Products

• 380370-56-9 2-benzenesulfonyl-2-diazo-N,N-diisopropyl-acetamide 
• 1202248-16-5 N,N-diisopropyl-2-phenylsulfonylpent-4-eneamide 
• 1262887-91-1 N,N-diisopropyl-2-phenylsulfonylhex-5-enamide 

Relevant academic research and scientific papers

Switching pathways: Room-temperature neutral solvolysis and substitution of amides

Stick or twist: By introducing steric hindrance at the nitrogen atom, stable linear amides bearing an electron-withdrawing α-substituent (Z=Ar, PhSO2, P(O)(OR)2, CN, or CO2R) can be induced to undergo solvolysis and substitution reactions through an elimination-addition mechanism (see picture). Key to this process is a low barrier to rotation around the amide bond and the α-substituentZ. Copyright

Allylation of prochiral C-nucleophiles catalyzed by the Pd(0)-(S)-(-)-BINAP complex

The allylation of prochiral C-nucleophiles catalyzed by the Pd(0)-(S)-(-)-BINAP complex (BINAP is 2,2′-bis(diphenylphosphino)-1, 1′-binaphthyl) was studied. The enantioselectivity of the allylation was found to be low.

Regio- and stereocontrol elements in Rh(II)-catalyzed intramolecular C-H insertion of α-diazo-α-(phenylsulfonyl)-acetamides

(matrix presnted) Intramolecular C-H insertion reaction of α-diazo-α-(phenylsulfonyl)acetamides proceeded with high regio- and stereoselectivities to afford highly functionalized y-lactams predominantly or exclusively. The high regioselectivity was attrib

Cyclofunctionalisation of epoxyalcohol derivatives. 4. Cyclisation of sulfonylacetate dianions: A synthesis of 'MeBMT'.

α,α-Dianions, derived from arenesulfonylacetate esters of 2,3-epoxyalcohols, cyclised to give 3-arenesulfonyl-4-(1-hydroxyalkyl)-γ-butyrolactones. Dianion fragmentation to regenerate the epoxyalcohol was a competing, substrate-dependent process. Sulfonylactone (9) was elaborated efficiently to an advanced intermediate for the unusual aminoacid 'MeBMT' (5), and also to stereodefined cyclopropane derivatives.