93251-18-4Relevant academic research and scientific papers
Development of a One-Pot Four C-C Bond-Forming Sequence Based on Palladium/Ruthenium Tandem Catalysis
Manick, Anne-Doriane,Berhal, Farouk,Prestat, Guillaume
supporting information, p. 194 - 197 (2018/01/17)
A one-pot four C-C bond-forming sequence has been developed using two distinct transition metal complexes. The sequence entails a double Pd-catalyzed allylic alkylation followed by a Ru-catalyzed ring-closing metathesis and a Pd-catalyzed Heck coupling. The use of various active methylene nucleophiles was examined with yields up to 76% (93% per C-C bond).
Synthesis of novel galactopyranosyl-derived spiro barbiturates
Ingle,Gaidhane,Dutta,Naha,Sengupta
, p. 661 - 671 (2007/10/03)
Malonic acid undergoes condensation readily with ureas to yield barbituric acids 2, which on bromination give 5,5-dibromobarbituric acids 3. Reaction of α-D-galactose with these 5,5-dibromo barbituric acids afforded 2,3-α-D-galactopyrano-1,4-dioxo-7,9-diaza-spiro[4,5]deca-6,8,10-triones 4. The structures of the products have been assigned on the basis of 1H NMR, 13C NMR, FAB-MS, optical activity, and elemental analysis. The title compounds are found to have antibacterial and antifungal activities.
A facile entry to fused pyrimidines: Preparation of pyrimido[4,5-b]quinoline and pyrido[2,3-d:6,5-d']dipyrimidine derivatives
Molina,Vilaplana,Pastor
, p. 827 - 829 (2007/10/02)
A number of pyrimido[4,5-b]quinolines 3 and pyrido[2,3-d:6,5-d']-dipyrimidines have been prepared by reaction of N,N'-disubstituted barbituric acids with the iminophosphorane derived from o-azidobenzaldehyde or 6-amino-5-formyl-1,3-dimethyluracil.
Ketene-S,N-acetals as Synthetic Intermediates for Heterocycles. Reaction of Ketene-S,N-acetals with Aryl Isocyanates
Takahata, Hiroki,Nakajima, Tomoko,Nakano, Masaharu,Tomiguchi, Akira,Yamazaki, Takao
, p. 4299 - 4308 (2007/10/02)
Reaction of ketene-S,N-acetals (1-6), which are useful synthetic intermediates for heterocycles, with aryl isocyanates (7) is described.Annulation of 1-3 and 4-6 with 7 in boiling toluene gave bicyclic (8-10) and monocyclic (11-13) uracil derivatives, res
