93252-65-4

Upstream product

• 2579-22-8 Phenylpropargyl aldehyde 
• 299-42-3 ephedrine 
• 1504-58-1 3-Phenyl-2-propyn-1-ol 

Downstream Products

• 93252-69-8 (2S,4S,5R)-3,4-Dimethyl-5-phenyl-2-((Z)-2-phenyl-but-1-enyl)-oxazolidine 
• 93252-62-1 (2S,4S,5R)-3,4-Dimethyl-5-phenyl-2-((E)-2-phenyl-but-1-enyl)-oxazolidine 
• 93252-68-7 (2S,4S,5R)-2-(2,2-Diphenyl-vinyl)-3,4-dimethyl-5-phenyl-oxazolidine 

Relevant academic research and scientific papers

Synthesis of 1,3-oxazolidines derived from ephedrine alkaloids. Crystal structure of (2S,4S,5S)-3,4-dimethyl-5-phenyl-2-phenylethynyl-1,3-oxazolidine

Substituted 1,3-oxazolidines were synthesized by condensation of phenylpropiolaldehyde with ephedrine alkaloids or by oxidative coupling of the latter with phenylpropargyl alcohol in the presence of manganese dioxide. The 1,3-oxazolidines were reacted with a Grignard reagent.

ETUDE D'UN MODELE D'INDUCTION ASYMETRIQUE: LES OXAZOLIDINES α,β-INSATUREES ISSUES DE L'EPHEDRINE

Various oxazolidines were prepared from ephedrine.It was shown that their formation is not general, the reaction is not always stereoselective and can lead to isomerization of the double bond of α,β-unsaturated aldehydes.Some of these oxazolidines were used in stereoselective preparation of β-alkyl aldehydes.