93270-42-9Relevant articles and documents
Rapid synthesis and lipase inhibition activity of some new benzimidazole and perimidine derivatives
Mente?e,Y?lmaz,Karaali,ülker,Kahveci
, p. 336 - 342 (2014/06/09)
This study presents a synthesis of new series of some benzimidazole, bisbenzimidazole and perimidine derivatives via microwave technique, which, leads to the good product yields and short reaction times. The structure of newly synthesized compounds was confirmed by 1H NMR and 13C NMR spectra. These compounds were screened for their lipase inhibition activity. Then, all compounds were evaluated with regard to pancreatic lipase activity, and some of the 2-substituted perimidines, bisperimidine and bisbenzimidazole derivatives showed lipase inhibition at various concentrations.
Synthesis and choleretic activity of 3-[2-(3-R', 4-R'', 5-R'''-benzyl)-5- R-benzimidazol-1-yl]-butanoic acids
Grella,Paglietti,Sparatore,Satta,Manca,Peana
, p. 21 - 35 (2007/10/02)
On the ground of the evidentiated choleretic activity of 3-[2- benzylbenzimidazol-1-yl]butanoic acid, 28 new acids were prepared in order to evaluate the influence of suitable substitutions in either C5 of heteroring or C3', C4', C5' of benzyl group in po
Synthesis and reactions of 2-amino-7,8-dimethoxy-1H-3-benzazepines. Competitive formation of 2-amino-1H-3-benzazepines VS. 2-benzylimidazoles
Robey,Copley-Merriman,Phelps
, p. 779 - 783 (2007/10/02)
A short synthesis of 2-amino-7,8-dimethoxy-1H-3-benzazepine (1a) from 3,4-dimethoxyphenylacetonitrile is reported. The synthesis of several other 2-amino-1H-3-benzazepines 1 is also discussed. Conditions which favor the formation of 1 versus the formation