93273-36-0Relevant academic research and scientific papers
Substituted guanidine derivatives and process for producing the same
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Page column 66, (2010/01/31)
A compound represented by the general formula (1): wherein each of R1, R2, R3, R4and R5is a hydrogen atom, an alkyl group, a substituted alkyl group, an alkenyl group, an alkynyl group, a cycloalkyl group, a cycloalkenyl group, a saturated heterocyclic group, an aromatic group, an acyl group or the like; each of Y1, Y2, Y3and Y4is a single bond, —CH2—, —O—, —CO— or the like, provided that at least two of Y1through Y4are independently a group other than a single bond; and Z may be absent, or one or more Zs may be present and are independently an alkyl group, a substituted alkyl group, an alkenyl group, an alkynyl group, a cycloalkyl group, a cycloalkenyl group, a saturated heterocyclic group, a halogen atom, a carboxyl group, an alkoxycarbonyl group, an aromatic group, an acyl group or the like, is useful as a therapeutic or prophylactic agent for diseases caused by the acceleration of the sodium/proton exchange transport system.
Dehydrogenation of 6-Alkylbenzocycloheptanes
Sen, P. K.,Lahiri, Sikha,Das, Tapan K.
, p. 821 - 824 (2007/10/02)
Acylation of benzene with α-alkylglutaric anhydrides gives separable isomeric mixtures of α-alkyl-γ-benzoylbutanoic acids (2; R1 = alkyl; R2 = H) and γ-alkyl-γ-benzoylbutanoic acids (2; R1 = H; R2 = alkyl).These acids (2) are converted into the title compounds (5) by the usual Wolff-Kishner reduction followed by polyphosphoric acid cyclization and Clemmensen reduction.Contrary to an earlier report , compounds (5) (R = Me, Et, n-Pr and n-Bu) on dehydrogenation with Pd-C give predominantly 1-methylnaphthalene together with small amounts of naphthalene, 1-alkylnaphthalene and 5-alkyl-1-methylnaphthalene.
