932747-64-3

Upstream product

• 932747-56-3 3-(6-chloroacetoxy-3-hydroxy-2,4,7,8-tetramethyl-11-oxo-4-vinyl-bicyclo[5.3.1]undec-1-yl)-propionic acid ethyl ester 
• 932747-54-1 3-{6-[(tert-butyl-diphenyl-silanyloxy)-acetoxy]-3-methoxymethoxy-2,4,7,8-tetramethyl-11-oxo-4-vinyl-bicyclo[5.3.1]undec-1-yl}-propionic acid 
• 932747-55-2 3-(3-hydroxy-6-hydroxyacetoxy-2,4,7,8-tetramethyl-11-oxo-4-vinyl-bicyclo[5.3.1]undec-1-yl)-propionic acid ethyl ester 

Downstream Products

• 932747-65-4 (3-amino-phenylsulfanyl)-acetic acid 7-[2-(tert-butoxycarbonylmethyl-carbamoyl)-ethyl]-5-hydroxy-1,4,6,10-tetramethyl-11-oxo-4-vinyl-bicyclo[5.3.1]undec-2-yl ester 
• 932747-78-9 3-{6-[(3-amino-phenylsulfanyl)-acetoxy]-3-hydroxy-2,4,7,8-tetramethyl-11-oxo-4-vinyl-bicyclo[5.3.1]undec-1-yl}-propionic acid 

Relevant academic research and scientific papers

Cyclopentanone ring-cleaved pleuromutilin derivatives

Ring-cleaved pleuromutilin derivatives comprised of a [5.3.1] bicyclic core structure have been synthesized and evaluated in vitro as antibacterial agents. Four of the compounds described were found to have MICs ≤ 4 μg/mL against marker strains of Strepto