93298-16-9Relevant academic research and scientific papers
Pd- mediated C-C bond formation with olefins and acetylenes on solid support: A scope and limitations study
Berteina, Sabine,Wendeborn, Sebastian,Brill, Wolfgang K.-D.,De Mesmaeker, Alain
, p. 676 - 678 (2007/10/03)
In this paper we report the scope and limitations of Pd(0)-mediated coupling reactions between aromatic iodides linked to a polystyrene resin and terminal acetylenes and olefins (Heck reactions). Optimized reaction conditions were evaluated with a number of different reagents. The optimized reaction conditions were frequently found to be superior to those previously reported in the literature and resulted in excellent yields of the products upon cleavage from the solid phase.
