93299-50-4 Usage
Uses
Used in Organic Synthesis:
2-Chloro-6-methoxy-3-quinolinecarbaldehyde oxime is used as a building block in organic synthesis for the creation of various heterocyclic compounds. Its unique structure allows for the formation of diverse chemical entities, making it a valuable component in the development of new organic compounds with potential applications in various fields.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2-chloro-6-methoxy-3-quinolinecarbaldehyde oxime is utilized as a key intermediate in the synthesis of new drugs. Its potential antimicrobial and antiprotozoal properties make it a promising candidate for the development of novel therapeutic agents to combat infectious diseases.
Used in Antimicrobial Applications:
2-Chloro-6-methoxy-3-quinolinecarbaldehyde oxime has been studied for its potential antimicrobial properties, making it a candidate for the development of new antibiotics. Its ability to target and inhibit the growth of various microorganisms could contribute to the fight against antibiotic-resistant bacteria and other pathogens.
Used in Antiprotozoal Applications:
2-CHLORO-6-METHOXY-3-QUINOLINECARBALDEHYDE OXIME has also been investigated for its antiprotozoal properties, indicating its potential use in the treatment of protozoan infections. Its ability to target and eliminate protozoan parasites could lead to the development of new drugs for the treatment of diseases caused by these organisms.
Used in Antioxidant and Anti-inflammatory Research:
2-Chloro-6-methoxy-3-quinolinecarbaldehyde oxime has been explored for its antioxidant and anti-inflammatory properties, which could make it a valuable tool in biomedicine and pharmacology. Its potential to combat oxidative stress and reduce inflammation may contribute to the development of new therapeutic agents for various inflammatory and oxidative stress-related conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 93299-50-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,3,2,9 and 9 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 93299-50:
(7*9)+(6*3)+(5*2)+(4*9)+(3*9)+(2*5)+(1*0)=164
164 % 10 = 4
So 93299-50-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H9ClN2O2/c1-16-9-2-3-10-7(5-9)4-8(6-13-15)11(12)14-10/h2-6,15H,1H3
93299-50-4Relevant academic research and scientific papers
Synthesis of new 3-(2-Chloroquinolin-3-yl)-5-phenylisoxazole derivatives via click chemistry approach
Ferna?ndez-Galleguillos, Carlos,Saavedra, Luis A.,Gutierrez, Margarita
, p. 365 - 371 (2014/02/14)
Herein, we report the synthesis of new substituted 3-(2-chloroquinolin-3- yl)-5-phenylisoxazole (3a-j) by click chemistry in good to moderate yields. This approach is based on the regioselective copper(I)-catalyzed cycloaddition between different nitrile oxides derived from 2-chloroquinoline- 3-carbaldehyde (2a-j) and phenylacetylene. Finally these derivatives were screened for their antibacterial evaluation in vitro against three Gram-negative clinical bacteria: Escherichia coli, Pseudomonas aeruginosa and Acinetobacter baumannii using standard methods.
An expeditious room temperature stirring method for the synthesis of isoxazolo[5,4-b]quinolines
Niralwad, Kirti S.,Shingate, Bapurao B.,Shingare, Murlidhar S.
experimental part, p. 805 - 807 (2012/01/03)
The synthesis of different derivatives of isoxazolo[5,4-b]quinoline by the cyclization reaction of various substituted oximes of quinoline using mild base at ambient temperature. The formation of isoxazolo[5,4-b]quinoline, as a consequence of cheaper and more readily available K2CO3 and DMF participating in the reaction, is documented. Copyright
Unusual Reaction of 2-Chloro-6,7-dialkoxyquinoline-3-aldoxime with Epichlorohydrin
Bhat, Neelima Balkrishen,Bhaduri, A.P.
, p. 431 - 434 (2007/10/02)
Unlike the reactions of 2-chloro- and 2-chloro-6-methoxyquinoline-3-aldoximes, the reaction of 2-chloro-6,7-dimethoxyquinoline-3-aldoxime (7) with epichlorohydrin gives 2-chloro-3-cyano-6,7-dimethoxyquinoline (13), 2-chloro-6,7-dimethoxyquinoline-3-aldoxime monomethyl ether (12), 6,7-dimethoxyisoxazoloquinoline (15), 2-chloro-6,7-dimethoxyquinoline-3-aldoxime-(2,3-epoxy)propyl ether (14), and 2-chloro-6,7-dimethoxyquinoline-3-aldoxime-(3'-methoxy-2'-hydroxy)propyl ether (16).However, 2-chloro-6,7-diethoxyquinoline-3-aldoxime (8) with epichlorohydrin affords the desired epoxy derivative (11) and a small quantity of 2-chloro-3-cyano-6,7-diethoxyquinoline (20).No definite reaction pathway could be delineated for the unusual reaction products of the reaction of 7 with epichlorohydrin.