93316-45-1

Usage

Molecular structure

A complex structure with an isoindole core and a hydroxyphenylpropan-2-yl group attached to the 2-position.

Type of compound

An isoindole derivative.

Physical state at room temperature

A solid.

Usage

Often used as a synthetic intermediate in various chemical reactions.

Potential applications

In pharmaceutical research and development.

Reasons for potential applications

Unique structure and properties.

Future research

Its precise uses and properties are likely to be investigated further in the scientific community.

Upstream product

• 150-30-1 Phenylalanine 
• 85-44-9 phthalic anhydride 
• 1795-98-8 rac-phenylalaninol 

Downstream Products

• 24419-74-7 3-phenyl-2-phthalimido-propionaldehyde 

Relevant academic research and scientific papers

Regioselective Fluorination of α-Hydroxy-β-aminophosphonates by Using PyFluor

We report a simple protocol for the synthesis of α-fluoro-β-aminophosphonates by the regioselective fluorination of α-hydroxy-β-aminophosphonates under mild conditions. The fluorination reactions were mediated by the PyFluor reagent and occurred with the retention of configuration. The main products of this reaction were a series of α-fluoro-β-aminophosphonates, which can be used as precursors in the preparation of medicinally important compounds (e.g., dipeptide analogues).

1-Aryl-2-acylamido-3-fluoro-1-propanols, methods for their use as antibacterial agents and compositions useful therefor

Described are D-(threo)-1-aryl-2-acylamido-3-fluoro-1-propanols, methods for their preparation, and methods for their use as antibacterial agents. Of particular interest are D-(threo)-1-p-nitrophenyl-2-dichloroacetamido-3-fluoro-1-propanol and D-(threo)-1-p-methylsulfonylphenyl-2-dichloroacetamido-3-fluoro-1-propanol and the corresponding 2-difluoroacetamido compounds which are the 3-fluoro-3-deoxy analogs of chloramphenicol, thiamphenicol, difluoroacetyl analog of chloramphenicol, and of fluorthiamphenicol, respectively, and which are active both against organisms sensitive to and resistant to the parent amphenicol antibiotics. Other particularly valuable antibacterial agents include the corresponding 2-(chlorofluoroacetamido)-, 2-dichlorodeuterioacetamido, 2-difluorodeuterioacetamido-, and the 2-(chlorofluorodeuterioacetamido)- derivatives of the foregoing 3-fluoro-3-deoxy amphenicols.