93326-45-5

Basic information

• Product Name: 1-NAPHTHALEN-1-YL-1H-INDAZOLE
• Synonyms: 1H-Indazole,1-(1-naphthyl)- (7CI)
• CAS NO: 93326-45-5
• Molecular Formula: C17H12 N2
• Molecular Weight: 244.29
• Mol File: 93326-45-5.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-NAPHTHALEN-1-YL-1H-INDAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-NAPHTHALEN-1-YL-1H-INDAZOLE(93326-45-5)
• EPA Substance Registry System: 1-NAPHTHALEN-1-YL-1H-INDAZOLE(93326-45-5)

Safety Data

• Hazardous Substances Data: 93326-45-5(Hazardous Substances Data)

Usage

Chemical classification

Synthetic cannabinoid

Structural relation

Related to popular recreational drug, synthetic marijuana

Receptor interaction

Potent agonist of cannabinoid receptors CB1 and CB2

Research use

Used to study effects of cannabinoid receptor activation

Psychoactive effects

Euphoria, relaxation, and altered perception

Comparison to natural cannabis

Effects are similar to those produced by natural cannabis

Adverse effects

Anxiety, paranoia, and rapid heart rate

Toxicity and overdose

Associated with numerous incidents of toxicity and overdose

Legal status

Classified as a controlled substance in many jurisdictions

Illegal activities

Illegal to manufacture, possess, or distribute for recreational use

Upstream product

• 6630-33-7 ortho-bromobenzaldehyde 
• 271-44-3 benzimidazole 
• 90-11-9 1-Bromonaphthalene 
• 2243-55-2 1-(1-naphthyl)hydrazine 

Relevant articles and documents

Gold modified zeolite: An efficient heterogeneous catalyst for n-arylation of indazole

We herein report N-arylation of indazole with aryl halides using gold modified zeolites (Au-zeolites) as an efficient catalytic system. Au-zeolites with three different gold loading were prepared by ion-exchange method and characterized by UV-visible diffuse reflectance spectroscopy (UV-DRS), transmission electron microscopy and energy-dispersive X-ray spectroscopy (TEM-EDX) and X-ray photoelectron spectroscopy (XPS). The Brunauer-Emmett-Teller (BET) and Langmuir surface areas of the prepared Au(5)-zeolite catalyst were found to be 644 and 929 m2g-1 respectively. Goldmodified zeolites performed as an efficient catalytic system for N-arylation of indazole using diverse aryl halides afforded N1 arylated products in appreciable yield under mild reaction conditions. The catalyst was reusable for at least five times with only a marginal loss of activity. This simple, effective and environmentally benign heterogeneous protocol provides a safer alternative to hazardous, corrosive and more polluting conventional catalysts.