93343-11-4

Basic information

• Product Name: 2,4,6-TRIFLUOROTOLUENE
• Synonyms: 2,4,6-TRIFLUOROTOLUENE;Benzene, 1,3,5-trifluoro-2-methyl- (9CI);2-Methyl-1,3,5-trifluorobenzene;2,4,6-Trifluorotolune
• CAS NO: 93343-11-4
• Molecular Formula: C7H5F3
• Molecular Weight: 146.11
• Product Categories: HALIDE;Halogen toluene
• Mol File: 93343-11-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 105-110
• Flash Point: 12.6 °C
• Appearance: /
• Density: 1.234 g/cm³
• CAS DataBase Reference: 2,4,6-TRIFLUOROTOLUENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6-TRIFLUOROTOLUENE(93343-11-4)
• EPA Substance Registry System: 2,4,6-TRIFLUOROTOLUENE(93343-11-4)

Safety Data

• Hazard Codes: F
• Hazardous Substances Data: 93343-11-4(Hazardous Substances Data)

Usage

General Description

2,4,6-Trifluorotoluene is a synthetic halogenated organic compound with a molecular formula of C7H5F3. It belongs to the family of organofluorides—compounds that contain a carbon-fluorine bond. As a volatile, colorless liquid, it's primarily used as a solvent or as an starting material in chemical synthesis. It can undergo nucleophilic aromatic substitutions, forming various other valuable chemical products via chemical reactions. Being a fluorinated compound, it's quite persistent and could be harmful for the environment, which makes its disposal and handling an important issue.

Upstream product

• 372-38-3 1,3,5-trifluorobenzene 
• 74-88-4 methyl iodide 

Relevant articles and documents

REACTIONS OF AROMATIC COMPOUNDS WITH NUCLEOPHILIC REAGENTS IN LIQUID AMMONIA. REACTION OF POLYFLUORINATED DERIVATIVES OF BENZENE WITH SODIUM AMIDE

Under the influence of sodium amide in liquid ammonia at a temperature no higher than -33 deg C pentafluorobenzene, 1,2,4,5-tetrafluorobenzene, and 1,3-difluorobenzene undergo deprotonation with the formation of fluorinated phenyl anions, which are resistant to the elimination of a fluoride ion and can be detected by the formation of the products from interaction with electrophiles (with the initial compound in the first case and with methyl iodide in the other two cases). 1,3,5-Trifluorobenzene behaves similarly in reaction with one equivalent of sodium amide, but with two equivalents of sodium amide this compound and 1,2,3,5-tetrafluorob enzene undergo substitution of a fluorine atom by an amino group with the formation of 3,5-di- and 3,4,5-trifluoroanilines respectively.This is clearly due to the double deprotonation of these compounds with the formation of polyfluorinated m-phenylene dianions, which are then converted with the elimination of a fluoride ion into the corresponding dehydrophenyl anions.