93343-12-5

Basic information

• Product Name: 1,3,5-TRIFLUORO-2,4-DIMETHYLBENZENE
• Synonyms: 1,3,5-TRIFLUORO-2,4-DIMETHYLBENZENE;2,4-Dimethyl-1,3,5-trifluorobenzene;2,4,6-Trifluoro-m-xylene
• CAS NO: 93343-12-5
• Molecular Formula: C8H7F3
• Molecular Weight: 160.14
• Mol File: 93343-12-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 132-133
• Flash Point: 32.6°C
• Appearance: /
• Density: 1.189g/cm³
• Vapor Pressure: 10.4mmHg at 25°C
• Refractive Index: 1.445
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1,3,5-TRIFLUORO-2,4-DIMETHYLBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,5-TRIFLUORO-2,4-DIMETHYLBENZENE(93343-12-5)
• EPA Substance Registry System: 1,3,5-TRIFLUORO-2,4-DIMETHYLBENZENE(93343-12-5)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 93343-12-5(Hazardous Substances Data)

Usage

General Description

1,3,5-Trifluoro-2,4-dimethylbenzene is a fluorinated aromatic compound with the chemical formula C8H7F3. It is a colorless liquid with a strong odor and is primarily used as a solvent or intermediate in the production of various chemicals, including pharmaceuticals and agrochemicals. It is also used in the manufacture of dyes and pigments, as well as in the production of polymers and resins. 1,3,5-Trifluoro-2,4-dimethylbenzene is flammable and should be handled with care, as it can pose a fire hazard. It is important to follow safety measures when working with this chemical, including wearing appropriate protective gear and ensuring proper ventilation.

InChI:InChI=1/C8H7F3/c1-4-6(9)3-7(10)5(2)8(4)11/h3H,1-2H3

Upstream product

• 372-38-3 1,3,5-trifluorobenzene 
• 74-88-4 methyl iodide 

Relevant articles and documents

REACTIONS OF AROMATIC COMPOUNDS WITH NUCLEOPHILIC REAGENTS IN LIQUID AMMONIA. REACTION OF POLYFLUORINATED DERIVATIVES OF BENZENE WITH SODIUM AMIDE

Under the influence of sodium amide in liquid ammonia at a temperature no higher than -33 deg C pentafluorobenzene, 1,2,4,5-tetrafluorobenzene, and 1,3-difluorobenzene undergo deprotonation with the formation of fluorinated phenyl anions, which are resistant to the elimination of a fluoride ion and can be detected by the formation of the products from interaction with electrophiles (with the initial compound in the first case and with methyl iodide in the other two cases). 1,3,5-Trifluorobenzene behaves similarly in reaction with one equivalent of sodium amide, but with two equivalents of sodium amide this compound and 1,2,3,5-tetrafluorob enzene undergo substitution of a fluorine atom by an amino group with the formation of 3,5-di- and 3,4,5-trifluoroanilines respectively.This is clearly due to the double deprotonation of these compounds with the formation of polyfluorinated m-phenylene dianions, which are then converted with the elimination of a fluoride ion into the corresponding dehydrophenyl anions.