933456-75-8Relevant academic research and scientific papers
Highly enantioselective Biginelli reaction promoted by chiral bifunctional primary amine-thiourea catalysts: Asymmetric synthesis of dihydropyrimidines
Wang, Yangyun,Yang, Haitao,Yu, Jipan,Miao, Zhiwei,Chen, Ruyu
supporting information; experimental part, p. 3057 - 3062 (2010/04/05)
The diastereospecific formation of dihydropyrimidines (DHPMs) has been achieved in moderate to high yields with up to 99% ee by a Biginelli reaction. The reaction was performed by using a combined catalyst consisting of a chiral bifunctional primary amine
Highly enantioselective Michael addition of malonates to nitroolefins catalyzed by chiral bifunctional tertiary amine-thioureas based on saccharides
Li, Xiao-Juan,Liu, Kun,Ma, Hai,Nie, Jing,Ma, Jun-An
experimental part, p. 3242 - 3246 (2009/06/25)
A series of saccharide-derived bifunctional tertiary amine-thioureas for the asymmetric Michael addition reaction have been designed and synthesized. The addition products between malonates and various nitroolefins were obtained in high yields (up to 99%)
Highly enantioselective Michael addition of aromatic ketones to nitroolefins promoted by chiral bifunctional primary amine-thiourea catalysts based on saccharides
Liu, Kun,Cui, Han-Feng,Nie, Jing,Dong, Ke-Yan,Li, Xiao-Juan,Ma, Jun-An
, p. 923 - 925 (2007/10/03)
(Chemical Equation Presented) A new class of thiourea catalysts have been developed which integrate saccharide and primary amine moieties into one small organic molecule. These simple catalysts are shown to be highly enantioselective for direct Michael ad
