933460-54-9Relevant academic research and scientific papers
Antiviral activity of triazine analogues of 1-(S)-[3-hydroxy-2- (phosphonomethoxy)propyl]cytosine (cidofovir) and related compounds
Kre?merová, Marcela,Holy, Antonín,Pískala, Alois,Masojídková, Milena,Andrei, Graciela,Naesens, Lieve,Neyts, Johan,Balzarini, Jan,De Clercq, Erik,Snoeck, Robert
, p. 1069 - 1077 (2007)
Treatment of 5-azacytosine sodium salt with diisopropyl [(2-chloroethoxy)methyl]phosphonate followed by removal of ester groups with BrSi(CH3)3 afforded 1-[2-(phosphonomethoxy)ethyl]-5- azacytosine (3). Reaction of 5-azacytosine with
AZACYTOSINE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS
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Page/Page column 16; 40, (2008/06/13)
The present invention provides 5-azacytosine derivatives with antiviral activity, specifically having viral replication inhibiting properties, more particularly in DNA viruses such as pox-, papilloma- and herpes viruses in humans. The invention also provi
